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Index > Protein center > Trps1(Gene name) > Mouse
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  • Trps1 (Gene name),
  • Zinc finger transcription factor Trps1 (Protein name ),  TRPS1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Trps1;
    Protein name:
    Zinc finger transcription factor Trps1;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with RNF4; regulates TRPS1 repressor activity. Interacts specifically with the activator form of GLI3 (GLI3A) but not with the repressor form (GLI3R).
    Function:
    Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    1281
    Sequence:
    50:
    MVRKKHPPLR | NVASEGEGQT | LEPTATESKV | SGKNKELSAD | QMSENTDQSD | 
    100:
    VAELNSKEEH | STHGQEPSSS | GKKDLQISGL | SEKAGFNYES | PSKGGSLVSF | 
    150:
    PHDEVTDRNM | LAFSSPAAGG | VCEPLKSPQR | AEADDPQDMA | CTPSGDSLET | 
    200:
    KEEHKMSPKA | TEETGPVQSG | QANCQGLSPV | SVASKNPQVP | SDGGVRLSKP | 
    250:
    KGDLLVNDNP | DPAPLSPELQ | DFKCNICGYG | YYGNDPTDLI | KHFRKYHLGL | 
    300:
    HNRTRQDAEL | DSKILALHNM | VQFSHSKDFQ | KVNRSVLSGV | LQDISSSRPA | 
    350:
    LLNGTYDVQV | TSGGTFIGIG | RKTPDCQGNT | KYFRCKFCNF | TYMGNSSTEL | 
    400:
    EQHFLQTHPN | KIKVSLPSSE | GVKPSEKNSN | KSIPALRASD | SGDVGKWQDK | 
    450:
    MTVKAGDDTP | VGYSVPIKPL | DSSRQNGTEA | TSYYWCKFCS | FSCESSSSLK | 
    500:
    LLEHYGKQHG | AVQSGGLNPE | LNDKLPRGSV | INQNDLAKSV | EGEPLTKPEK | 
    550:
    GLSGAKKKDF | PSKGAEDNMV | TSYNCQFCDF | RYSKSHGPDV | IVVGPLLRHY | 
    600:
    QQLHNIHKCT | IKHCPFCPRG | LCSPEKHLGE | ITYPFACRKS | NCSHCALLLL | 
    650:
    HLSPGVAGSS | RVKHQCHQCS | FSTPDVDVLL | FHYETVHESQ | ASDVKQEANH | 
    700:
    LLGSDGQQAV | RDSKEHSCTK | CDFITQVEEE | ISRHYRRAHS | CYKCRQCSFT | 
    750:
    AADTQSLLEH | FNTVHCQEQE | ITTANGEEGG | HAIPTIKEEP | KIDLKVYSLL | 
    800:
    NPDSKMGETV | PESIVKREKL | DDKEGLKDKI | WTESSTDDLR | GVAWRGADIL | 
    850:
    RGSPSYTQAS | LGLLTPVSSS | QEQTKTLRDS | PNVEAAHLAR | PMYGLAVDTK | 
    900:
    GFLQGAPAGS | EKSASLTQQY | PASGESKTKD | ESQSLLRRRR | GSGVFCANCL | 
    950:
    TTKTSLWRKN | ANGGYVCNAC | GLYQKLHSTP | RPLNIIKQNN | GEQIIRRRTR | 
    1000:
    KRLNPEALQA | EQLNKQQRGS | GEEQVNGSPL | ERRSEDHLSE | SHPREIPLPS | 
    1050:
    LSKYEAQGSL | TKSHSAQQPV | LVSQALDIHK | RMQPLHIQIK | SPQESTGDPG | 
    1100:
    NSSSVSDGKG | SSERGSPIEK | YMRPAKHPNY | SPPGSPIEKY | QYPLFGVPFV | 
    1150:
    HNDFQSEADW | LRFWSKYKLS | VPGNPHYLSH | VPGLPNPCQN | YVPYPTFNLP | 
    1200:
    PHFSAVGSDN | DIPLDLAIKH | SRPGPTANGA | SKEKTKAPPT | VKNEDPLNVV | 
    1250:
    KTEKVDRSTQ | DELSTKCVHC | GIVFLDEVMY | ALHMSCHGDS | GPFQCSICQH | 
    1281:
    LCTDKYDFTT | HIQRGLHRNN | AQAEKNGKPK | E
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Zinc finger transcription factor Trps1
    Cat.:
    E3470h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Zinc finger transcription factor Trps1
    Cat.:
    E3470m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Zinc finger transcription factor Trps1
    Cat.:
    U3470m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Zinc finger transcription factor Trps1
    Cat.:
    U3470h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Zinc finger transcription factor Trps1
    Cat.:
    P3470Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Zinc finger transcription factor Trps1
    Cat.:
    P3470Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Zinc finger transcription factor Trps1
    Monoclonal Antibody for Mouse Zinc finger transcription factor Trps1
    Protein for Mouse Zinc finger transcription factor Trps1
    Protein for Mouse Zinc finger transcription factor Trps1

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1."
      Malik T.H. , Shoichet S.A. , Latham P. , Kroll T.G. , Peters L.L. , Shivdasani R.A.
      EMBO J.20:1715-1725(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;DEVELOPMENTAL STAGE
      tissue: Fetal intestine.
    2. 2.
      "The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor."
      Kaiser F.J. , Moeroey T. , Chang G.T. , Horsthemke B. , Luedecke H.J.
      J. Biol. Chem.278:38780-38785(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RNF4
    3. 3.
      "Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3."
      Wuelling M. , Kaiser F.J. , Buelens L.A. , Braunholz D. , Shivdasani R.A. , Depping R. , Vortkamp A.
      Dev. Biol.328:40-53(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH GLI3
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